William D Foulkes Selected Research

MicroRNAs (MicroRNA)

9/2023	DICER1 platform domain missense variants inhibit miRNA biogenesis and lead to tumor susceptibility.
1/2023	miRNA biogenesis and inherited disorders: clinico-molecular insights.
1/2021	DICER1-associated embryonal rhabdomyosarcoma and adenosarcoma of the gynecologic tract: Pathology, molecular genetics, and indications for molecular testing.
1/2021	Endometrial Stem/Progenitor cell (ES/PC) Marker Expression Profile in Adenosarcoma and Endometrial Stromal Sarcoma.
1/2020	DGCR8 microprocessor defect characterizes familial multinodular goiter with schwannomatosis.
1/2019	Mesenchymal Hamartoma of the Liver and DICER1 Syndrome.
1/2018	Anaplastic sarcomas of the kidney are characterized by DICER1 mutations.
4/2013	Germ-line DICER1 mutations do not make a major contribution to the etiology of familial testicular germ cell tumours.
9/2012	Exploring the endocrine manifestations of DICER1 mutations.
1/2012	Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers.

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William D Foulkes Research Topics

Disease

113	Neoplasms (Cancer) 03/2024 - 12/2002
79	Breast Neoplasms (Breast Cancer) 04/2024 - 10/2002
23	Ovarian Neoplasms (Ovarian Cancer) 02/2024 - 11/2003
10	Prostatic Neoplasms (Prostate Cancer) 01/2020 - 12/2002
7	Sarcoma (Soft Tissue Sarcoma) 03/2024 - 06/2017
7	Adenocarcinoma 11/2023 - 09/2005
6	Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer) 11/2023 - 04/2006
6	Carcinoma (Carcinomatosis) 11/2023 - 04/2007
6	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 02/2002
5	Pleuropulmonary blastoma 03/2024 - 01/2011
5	Small Cell Carcinoma 10/2023 - 04/2015
4	Melanoma (Melanoma, Malignant) 05/2024 - 12/2002
4	Endometrial Neoplasms (Endometrial Cancer) 08/2023 - 12/2002
4	Fallopian Tube Neoplasms 01/2022 - 07/2006
4	Neoplasm Metastasis (Metastasis) 03/2013 - 04/2009
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2023 - 01/2019
3	Polyps 09/2021 - 03/2009
3	Triple Negative Breast Neoplasms 01/2019 - 12/2008
3	Carcinogenesis 01/2011 - 04/2002
3	Colorectal Neoplasms (Colorectal Cancer) 01/2009 - 02/2003
2	Turcot syndrome 11/2023 - 01/2019
2	Brain Neoplasms (Brain Tumor) 01/2023 - 01/2021
2	Dementia (Dementias) 01/2022 - 10/2020
2	Cysts 01/2022 - 01/2018
2	Embryonal Rhabdomyosarcoma 01/2021 - 06/2017
2	Adenosarcoma 01/2021 - 01/2021
2	Familial Breast Cancer 05/2020 - 10/2005
2	Hypersensitivity (Allergy) 01/2019 - 04/2013
2	Genetic Predisposition to Disease (Genetic Predisposition) 01/2018 - 01/2018
2	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 01/2018 - 12/2010
2	medullary Thyroid cancer 01/2018 - 03/2004
2	Second Primary Neoplasms (Neoplasms, Second) 01/2017 - 01/2005
2	Sertoli-Leydig Cell Tumor 07/2016 - 01/2012
2	Candidiasis (Moniliasis) 04/2016 - 07/2014
2	autosomal recessive Candidiasis familial chronic mucocutaneous 04/2016 - 07/2014
2	Adenoma (Adenomas) 01/2006 - 09/2005
2	Squamous Cell Carcinoma of Head and Neck 07/2004 - 04/2002

Drug/Important Bio-Agent (IBA)

30	Proteins (Proteins, Gene)FDA Link 11/2023 - 02/2004
21	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 02/2003
19	Estrogen ReceptorsIBA 03/2024 - 10/2002
15	Ribonucleases (Ribonuclease)IBA 09/2023 - 01/2012
13	Tamoxifen FDA LinkGeneric 09/2023 - 10/2002
11	MicroRNAs (MicroRNA)IBA 09/2023 - 11/2011
9	Cyclin D1IBA 12/2022 - 01/2004
7	ChromatinIBA 01/2024 - 12/2015
7	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2008
7	Keratin-5 (Keratin 5)IBA 01/2017 - 10/2003
6	Dihydrotachysterol (AT 10)IBA 03/2024 - 10/2003
6	Poly(ADP-ribose) Polymerase InhibitorsIBA 01/2022 - 08/2008
5	beta CateninIBA 12/2022 - 01/2004
5	Ribonuclease III (RNase III)IBA 06/2017 - 01/2011
5	Hormones (Hormone)IBA 05/2015 - 06/2003
4	ErbB Receptors (EGF Receptor)IBA 01/2023 - 10/2008
4	Oral ContraceptivesIBA 01/2022 - 12/2002
4	PlatinumIBA 10/2020 - 01/2006
4	olaparibIBA 01/2020 - 10/2011
4	Progesterone Receptors (Progesterone Receptor)IBA 02/2019 - 04/2009
3	Sucrose (Saccharose)IBA 01/2024 - 11/2016
3	Calbindin 2IBA 12/2022 - 05/2015
3	Inhibins (Inhibin)IBA 12/2022 - 05/2015
3	RNA (Ribonucleic Acid)IBA 12/2021 - 10/2011
3	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 10/2011
3	Prostate-Specific Antigen (Semenogelase)IBA 12/2019 - 01/2018
3	Cadherins (E-Cadherin)IBA 01/2017 - 05/2005
3	Indicators and Reagents (Reagents)IBA 09/2014 - 09/2009
3	Epidermal Growth Factor (EGF)IBA 09/2014 - 05/2010
3	Cyclin EIBA 10/2008 - 02/2004
2	AntigensIBA 03/2024 - 01/2022
2	Pregnenolone Carbonitrile (PCN)IBA 03/2024 - 01/2018
2	Oncogene Proteins (Oncogene Protein)IBA 11/2023 - 02/2013
2	Raloxifene Hydrochloride (Evista)FDA Link 09/2023 - 05/2008
2	Tyrosine Kinase InhibitorsIBA 01/2023 - 01/2018
2	MyogeninIBA 09/2021 - 01/2020
2	Immune Checkpoint InhibitorsIBA 01/2021 - 01/2020
2	CarcinogensIBA 01/2020 - 03/2009
2	Messenger RNA (mRNA)IBA 01/2020 - 01/2017
2	A-Form DNA (A-DNA)IBA 01/2019 - 01/2011
2	Calcibiotic Root Canal SealerIBA 01/2019 - 01/2009
2	imidazole mustard (BIC)IBA 12/2018 - 11/2009
2	Estrogens (Estrogen)FDA Link 01/2018 - 12/2008
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 04/2016 - 07/2014
2	Factor VIII (Coagulation Factor VIII)IBA 06/2012 - 12/2011
2	EndoribonucleasesIBA 01/2012 - 01/2011
2	Phenobarbital (Luminal)FDA Link 01/2011 - 12/2010
2	AntralIBA 01/2006 - 09/2005
2	ORALIT (ORS)IBA 10/2005 - 12/2003
1	Sunscreening Agents (Sunscreens)IBA 05/2024

Therapy/Procedure

29	Ovariectomy (Oophorectomy) 02/2024 - 06/2004
21	Therapeutics 03/2024 - 04/2002
18	Mastectomy (Mammectomy) 04/2024 - 06/2004
15	Drug Therapy (Chemotherapy) 08/2023 - 02/2003
11	Salpingo-oophorectomy 02/2024 - 07/2006
5	Prophylactic Mastectomy 10/2022 - 08/2005
4	Radiotherapy 04/2024 - 01/2005
4	Hormone Replacement Therapy (Therapy, Hormone Replacement) 06/2021 - 07/2013
3	Immunotherapy 03/2024 - 01/2020
3	Chemoprevention 09/2023 - 02/2002
3	Adjuvant Chemotherapy 11/2009 - 02/2003
2	Gynecologic Surgical Procedures (Gynecologic Surgery) 12/2008 - 11/2003
2	Colectomy 01/2006 - 09/2005